MCP server and Claude Plugin for a full ENCODE Project genomic data and analysis toolkit — search, download, track, and analyze functional genomics experiments
Config is the same across clients — only the file and path differ.
{
"mcpServers": {
"encode-toolkit": {
"command": "<see-readme>",
"args": []
}
}
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MCP server and Claude Plugin for a full ENCODE Project genomic data and analysis toolkit — search, download, track, and analyze functional genomics experiments
No automated test available for this server. Check the GitHub README for setup instructions.
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Search ENCODE, cross-reference 14 databases, run 7 analysis pipelines, and generate publication-ready methods — all from natural language in Claude Code.
Start from ENCODE but go everywhere: discover histone peaks, cross-reference with GWAS variants, check ClinVar pathogenicity, pull GTEx expression, analyze TF binding motifs from JASPAR, run pipelines, and generate publication-ready methods with full provenance — in one conversation.
If you use ENCODE-Toolkit, please cite:
Alex M. Mawla. (2026). ENCODE-Toolkit: an MCP server, Claude plugin, and skills suite for ENCODE genomic data access and analysis. Zenodo. https://doi.org/10.5281/zenodo.18917511
@software{mawla_2026_encode_toolkit,
author = {Mawla, Alex M.},
title = {ENCODE-Toolkit: an MCP server, Claude plugin, and skills suite for ENCODE genomic data access and analysis},
year = {2026},
publisher = {Zenodo},
doi = {10.5281/zenodo.18917511},
url = {https://doi.org/10.5281/zenodo.18917511}
}
Start a new Claude Code session and enter:
/plugin marketplace add ammawla/encode-toolkit
/plugin install encode-toolkit
That's it. All 20 tools, 47 skills, and the MCP connector are now available.
If you only need the 20 MCP tools without the 47 workflow skills:
claude mcp add encode -- uvx encode-toolkit