Biomedical MCP server: genes, variants, trials, literature, patents, optional SQL/R/biowasm tools.
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io.github.yeyuan98/biomcp-ts is an MCP server that biomedical MCP server: genes, variants, trials, literature, patents, optional SQL/R/biowasm tools. Its tool list has not been published yet over stdio and sse, requires no API key, and scores 63/100 on MCPpedia's security, maintenance and efficiency rubric.
Config is the same across clients - only the file and path differ.
{
"mcpServers": {
"io-github-yeyuan98-biomcp-ts": {
"args": [
"-y",
"biomcp"
],
"command": "npx"
}
}
}Are you the author?
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Biomedical MCP server: genes, variants, trials, literature, patents, optional SQL/R/biowasm tools.
This server supports HTTP transport. Be the first to test it - help the community know if it works.
Five weighted categories - click any category to see the underlying evidence.
No known CVEs.
Checked biomcp against OSV.dev.
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Democratizing agentic access to bioinformatics and biopharmaceutical databases and analyses.
npx -y biomcp doctor # diagnose a machine: Node gate, config health, feature gates, peer deps
npx biomcp # zero-config stdio MCP server (this is what MCP clients run); Node >= 22.13
Setup is guided in docs/AGENT-INSTALL.md — a one-minute start, copy-paste config entries for Claude Desktop, Claude Code, Codex, and OpenCode (one canonical pinned command covering every feature), biomcp doctor as the single troubleshooting entry point, and agent-friendly paths for API keys and optional features.
Multiple agents on one machine: biomcp enforces arXiv's Terms-of-Use rate limit (1 request / 3 s) per process. When running multiple biomcp MCP instances on one machine (e.g., one stdio instance per agent), rate limits are not coordinated across processes, and arXiv's TOU applies to all your machines in aggregate. For multi-agent single-machine deployments, run a single shared biomcp serve daemon (see docs/SELF-HOSTING.md) so all agents share one process and one global rate limiter.
Full tool schemas (params, enums, defaults) live in src/server/README.md.
| Tool | Description |
|---|---|
gene_search | Search genes by symbol, name, or keyword with chromosome filter |
gene_get | Get detailed gene info by HGNC symbol with optional sections (core, pathways, protein, ontology, go, interactions, expression, protein_atlas, constraint, druggability, dosage_sensitivity, clinical_evidence, disease_associations, diseases, funding). Set smart=true to auto-resolve gene aliases (e.g., "HER2" → "ERBB2") |
gene_diseases | Get diseases associated with a gene (DisGeNET / OpenTargets) |
gene_drugs | Find drugs targeting a gene (OpenTargets; envelope { results, warnings?, errors? } — OpenTargets failures and unresolved genes ride in errors[], never as inline rows) |
gene_trials | Find clinical trials for a gene |
gene_articles | Find articles about a gene (federated across PubMed, EuropePMC, Semantic Scholar, arXiv, PubTator, LitSense; envelope { results, warnings?, errors? } — per-backend failures ride in errors) |
gene_enrich | Pathway enrichment analysis for a gene list (Reactome) |
| Tool | Description |
|---|---|
variant_search | Search variants by rsid, HGVS, gene, ClinVar significance, frequency, CADD |